Ahmed Massoud

The SLC7A11 Thermostat: A Molecular Signaling Switch Between Ferroptosis and Disulfidptosis in Neurodegenerative Disease

This review highlights the role of SLC7A11 as a key molecular regulator linking ferroptosis and disulfidptosis in neurodegenerative diseases. It examines how redox balance, cystine metabolism, and NADPH availability influence this dual cell-death pathway and explores the potential implications for understanding disease mechanisms and developing targeted neuroprotective strategies.

Neuroprotective effects of Moringa oleifera leaf extract via potential NF-κB modulation in cuprizone-induced demyelination in rats: Integrated in vivo and in silico evidence

This article highlights the neuroprotective potential of Moringa oleifera leaf extract against cuprizone-induced demyelination through its antioxidant, anti-inflammatory, and neurobehavioral effects, potentially mediated by modulation of the NF-κB pathway.

Repurposing approved drugs as ferroptosis modulators: a critical review of clinical trials in cancer and neurodegeneration

This review highlights the potential of ferroptosis modulation as a therapeutic strategy in cancer and neurodegenerative diseases. It examines clinical evidence from repurposed approved drugs with ferroptosis-modulating properties and explores the key barriers that have limited successful clinical translation.

Snippets from My Master’s Journey

Throughout my master’s journey, I have been fortunate to grow academically and professionally. This …

Betanin from 𝘉𝘦𝘵𝘢 𝘷𝘶𝘭𝘨𝘢𝘳𝘪𝘴 Attenuates Complete Freund’s Adjuvant-Induced Inflammatory Pain: Integrated Preclinical and In Silico Insights

This article highlights the analgesic potential of betanin, a natural pigment derived from Beta vulgaris, in inflammatory pain through anti-inflammatory, antioxidant, and pain-associated miRNA-related effects.

Integrating Single-Cell Sequencing and Proteomics to Unravel Stem Cell Heterogeneity: Implications for Precision Regenerative Medicine

This review emphasizes the role of combined single-cell sequencing and proteomics approaches in decoding stem cell heterogeneity, offering advanced insights into cell fate decisions and supporting the development of precision regenerative medicine strategies.

Harnessing Adipose Ferroptosis: A Promising Novel Pathway for Obesity Treatment

This review summarizes the potential of targeting ferroptosis-iron-dependent lipid peroxidation-as a novel strategy for treating obesity and its metabolic complications through mechanisms different from traditional interventions.

Scientific Lecture at Sci. Green Camp, Alexandria University

As part of ongoing efforts to promote research skills among undergraduate students and researchers, …

GPA Calculator, Built for Faculty Students

When I was in the college, I always needed to track my GPA after each semester and plan for the next …